The news comes only six weeks after owner Balfour Beatty, who acquired the gateway in 2008, announced its intention to find a buyer on August 28, 2014, as it had decided to end its involvement in running regional airports.
A statement from the corporate affairs department, yesterday said: "The airport operation has been making a loss for a number of years and unfortunately there is no option for the company other than to close.
"This is a very sad day for the airport which has a proud aviation history and a loyal, appreciative customer following. We would like to thank all our dedicated staff who have delivered exceptional service to passengers for many years.
"The airport will remain open to the public until October 15, 2014 and we will endeavour to maintain operations as normal until this date, after which time commercial flights will cease."
Airlines operating flights include Jet2.com, Sotbart Air and Citywing, and the airport is recommending that passengers contact their airline to confirm travel arrangements.
The airport statement continues: "While the sales process announced at the end of August was a final attempt to secure the future of the airport, the airport's management had spent many months prior to this announcement approaching organisations with a potential interest in the airport in an attempt to find a buyer.
"Work is currently underway with the independent aviation businesses and tenants at the airport to understand if their operations can continue in the future.
"Working in partnership with the local authorities, regeneration plans are also being developed which will be designed to create future employment and sustainable economic development opportunities for Blackpool and the Fylde Coast."
There are about 110 staff employed at Blackpool International Airport, which last year, handled 262,000 passengers, an 11.9% rise of 27,000 on 2012, but still below its peak of more than 500,000 in 2007.